abstract::Osteoarthritis (OA) is a rheumatic disease common in the elderly. AGEs are the end products of glycation reactions and play an important role in the development of OA. Etomidate is a general anesthesia-inducing agent recently reported to exert significant anti-inflammatory effects. The present study aims to explore th...
journal_title:Bioengineeredpub_type: 杂志文章
doi:10.1080/21655979.2021.1951926
更新日期:2021-12-01 00:00:00
abstract::In Greenland, the universal parenting programme MANU was developed in 2016. After documenting the initial years of MANU's implementation, this study aimed to identify implementation determinants focusing on i) which context MANU was conceptualised in and how it was developed and ii) how MANU was implemented and initia...
journal_title:International journal of circumpolar healthpub_type: 杂志文章
doi:10.1080/22423982.2021.1938443
更新日期:2021-12-01 00:00:00
abstract::Hepatoblastoma is a kind of extreme malignancy frequently diagnosed in children. Although surgical resection is considered as the first-line treatment for hepatoblastoma, a relatively large population of patients have lost the preferred opportunity for surgery. Administration of locoregional ablation enables local tum...
journal_title:Bioengineeredpub_type: 杂志文章
doi:10.1080/21655979.2021.1945521
更新日期:2021-12-01 00:00:00
abstract:BACKGROUND:The main risk factor for uterine scar dehiscence is a previous caesarean section. Better characterisation of the ultrasonographic features of uterine scar dehiscence may improve preoperative diagnostic accuracy in pregnant women with a caesarean scar. This study aimed to evaluate the ultrasonographic feature...
journal_title:Annals of medicinepub_type: 杂志文章
doi:10.1080/07853890.2021.1959049
更新日期:2021-12-01 00:00:00
abstract::We previously found that a nanoparticle constructed with an antigen, benzalkonium chloride (BK) and γ-polyglutamic acid (γ-PGA) showed high Th1 and Th2-type immune induction after subcutaneous administration. For prophylaxis of respiratory infections, however, mucosal immunity should be induced. In this study, we inve...
journal_title:Drug deliverypub_type: 杂志文章
doi:10.1080/10717544.2021.1955040
更新日期:2021-12-01 00:00:00
abstract:BACKGROUND:The COVID-19 pandemic has had a substantial impact on primary care throughout Europe and globally. OBJECTIVES:This review aims to ascertain how the pandemic has impacted primary care service provision/patients and to examine strategies to mitigate these impacts. METHODS:The scoping review framework compris...
journal_title:The European journal of general practicepub_type: 杂志文章
doi:10.1080/13814788.2021.1946681
更新日期:2021-12-01 00:00:00
abstract::Chemotherapy with combination drugs has become one of the most commonly used cancer prevention treatments, with positive clinical results. The goal of this study was to develop compostable polymeric nanomaterials (NMs) for the delivery of puerarin (PRN) and 5-fluorouracil (5FU), as well as to investigate the anticance...
journal_title:Drug deliverypub_type: 杂志文章
doi:10.1080/10717544.2021.1934187
更新日期:2021-12-01 00:00:00
abstract::Inflammation and oxidative stress are crucial in ischemic stroke. Ephedrine (EPH) has been proven to have anti-inflammatory and anti-oxidative stress effects. The present study analyzes whether EPH possessed neuroprotective effects and explored the underlying mechanisms of EPH based on an experimental model of middle ...
journal_title:Bioengineeredpub_type: 杂志文章
doi:10.1080/21655979.2021.1953218
更新日期:2021-12-01 00:00:00
abstract::To identify how circular RNA circRNA_0082835 impacts melanoma cells and lymphatic metastasis to observe whether it exerts effects through its action mechanism of sponging microRNA miR-429. Clinical baseline information was collected, and clinical samples were used for detection on circRNA_0082835 and EZH2. The express...
journal_title:Bioengineeredpub_type: 杂志文章
doi:10.1080/21655979.2021.1953822
更新日期:2021-12-01 00:00:00
abstract::The model of immune-related lncRNA pairs (IRLPs) seems to be an available predictor in lung adenocarcinoma (LUAD) patients. The aim of our study was to construct a model with IRLPs to predict the survival status and immune landscape of LUAD patients. Based on TCGA-LUAD dataset, a risk assessment model with IRLPs was e...
journal_title:Bioengineeredpub_type: 杂志文章
doi:10.1080/21655979.2021.1953215
更新日期:2021-12-01 00:00:00
abstract::Mathematical models for the action potential (AP) generation of the electrically excitable cells including the heart are involved different mechanisms including the voltage-dependent currents with nonlinear time- and voltage-gating properties. From the shape of the AP waveforms to the duration of the refractory period...
journal_title:Channels (Austin, Tex.)pub_type: 杂志文章
doi:10.1080/19336950.2021.1940628
更新日期:2021-12-01 00:00:00
abstract::MicroRNAs exert crucial effects in the drug resistance. The purpose of this research was to investigate the miR-25-3p effects on DDP resistance in NSCLC. We used RT-qPCR to evaluate the expression of miR-25-3p. Cell growth was determined using MTS assay. Cellular bio-activity was analyzed via Colony formation, Annexin...
journal_title:Bioengineeredpub_type: 杂志文章
doi:10.1080/21655979.2021.1939577
更新日期:2021-12-01 00:00:00
abstract::Extracellular vesicles (EVs) are nanovesicles released by various cell types. EVs are known for cell-to-cell communications and have potent biological activities. Despite great progress in recent years for studies exploring the potentials of EVs for early disease detection, therapeutic application and drug delivery, d...
journal_title:Drug deliverypub_type: 杂志文章
doi:10.1080/10717544.2021.1951896
更新日期:2021-12-01 00:00:00
abstract::Purpose: Prior research provides limited information on the roles that leisure can play among Western international students studying in Eastern countries. Exploring this directional difference can provide its implications for Western international student support. Therefore, the purpose of this study is to explore le...
journal_title:International journal of qualitative studies on health and well-beingpub_type: 杂志文章
doi:10.1080/17482631.2021.1945725
更新日期:2021-12-01 00:00:00
abstract::The high contamination by the SARS-Cov-2 virus has led to the search for ways to minimize contagion. Masks are used as part of a strategy of measures to suppress transmission and save lives. However, they are not sufficient to provide an adequate level of protection against COVID-19. Activated charcoal has an efficien...
journal_title:Journal of nanoscience and nanotechnologypub_type: 杂志文章
doi:10.1166/jnn.2021.19525
更新日期:2021-12-01 00:00:00
abstract::Cadmium sulfide nanoparticles (CdS NPs) were synthesized by using cadmium acetate and thiourea as precursors and sodium oleate as the surfactant under different cadmium acetate concentrations in anhydrous ethanol. Cadmium (Cd) precursor concentration greatly affected the nucleation-growth of CdS NPs. In extremely dilu...
journal_title:Journal of nanoscience and nanotechnologypub_type: 杂志文章
doi:10.1166/jnn.2021.19504
更新日期:2021-12-01 00:00:00
abstract::We examined the effects of oral administration of L-citrulline (L-Cit) on plasma metabolic hormones and biochemical profile in broilers. Food intake, water intake, and body temperature were also analyzed. After dual oral administration (20 mmol/head/administration) of L-Cit, broilers were exposed to a high ambient tem...
journal_title:Animal science journal = Nihon chikusan Gakkaihopub_type: 杂志文章
doi:10.1111/asj.13578
更新日期:2021-12-01 00:00:00
abstract::We studied the effects of wolfberry and astragalus extract on the growth performance, carcass traits, and meat quality of Tibetan fragrant pigs, and we want to explain the mechanism of the difference from the level of RNA Seq. Twelve healthy 120-day-old Tibetan fragrant pigs weighing 35 ± 2 kg were divided randomly in...
journal_title:Animal science journal = Nihon chikusan Gakkaihopub_type: 杂志文章
doi:10.1111/asj.13581
更新日期:2021-12-01 00:00:00
abstract::Candida albicans, which can cause superficial and life-threatening systemic infections, is the most common opportunistic fungal pathogen in the human microbiome. The two-component system is one of the most important C. albicans signal transduction pathways, regulating the response to oxidative and osmotic stresses, ad...
journal_title:Virulencepub_type: 杂志文章
doi:10.1080/21505594.2021.1949883
更新日期:2021-12-01 00:00:00
abstract::Greenlandic traditional nutrition was an almost exclusive meat dietary pattern. Høygaard et al. stayed in East-Greenland between August 1936 and August 1937. The four members of the expedition resided in Tasisaq and recorded nutritional intake by residing in families. However, data were analysed on a household level. ...
journal_title:International journal of circumpolar healthpub_type: 杂志文章
doi:10.1080/22423982.2021.1951471
更新日期:2021-12-01 00:00:00
abstract::The significant role of Tris(2,2,2-trifluoroethyl) phosphite (TTFP) as an efficient additive during cycling of the layered nanostructured LiNi0.1Mg0.1Co0.8O₂ and olivine LiFePO₄ cathode materials in EC/DMC and 1M LiPF6 electrolyte for Li-ion battery are extensively investigated in this work. The electrochemical charac...
journal_title:Journal of nanoscience and nanotechnologypub_type: 杂志文章
doi:10.1166/jnn.2021.19322
更新日期:2021-12-01 00:00:00
abstract::Ionic liquids are an interesting class of materials that have recently been utilized as chemotherapeutic agents in cancer therapy. Aniline blue, a commonly used biological staining agent, was used as a counter ion to trihexyltetradecylphosphonium, a known cytotoxic cation. A facile, single step ion exchange reaction w...
journal_title:Journal of nanoscience and nanotechnologypub_type: 杂志文章
doi:10.1166/jnn.2021.19535
更新日期:2021-12-01 00:00:00
abstract::Bearings play a vital role in the operation of a two-axis system. Long-term bearing use inevitably produce bubbles and frictional damage. Therefore, the protection of bearings is critical for the stable operation of a two-axis system. In this study, a TiO₂ nanofilm is used to physically protect a bearing. The discreti...
journal_title:Journal of nanoscience and nanotechnologypub_type: 杂志文章
doi:10.1166/jnn.2021.19506
更新日期:2021-12-01 00:00:00
abstract::A Hamiltonian Monte Carlo algorithm is a Markov chain Monte Carlo method, and the method has a potential to improve estimating parameters effectively. Hamiltonian Monte Carlo is based on Hamiltonian dynamics, and it follows Hamilton's equations, which are expressed as two differential equations. In the sampling proces...
journal_title:Animal science journal = Nihon chikusan Gakkaihopub_type: 杂志文章
doi:10.1111/asj.13575
更新日期:2021-12-01 00:00:00
abstract::Angiotensin I-converting enzyme 2 (ACE2), type II transmembrane serine protease 2 and 4 (TMPRSS2 and TMPRSS4) are important receptors for SARS-CoV-2 infection. In this study, the full-length tree shrewACE2 gene was cloned and sequenced, and its biological information was analyzed. The expression levels of ACE2, TMPRSS...
journal_title:Bioengineeredpub_type: 杂志文章
doi:10.1080/21655979.2021.1940072
更新日期:2021-12-01 00:00:00
abstract::Mutual fidelity and partner reduction have been identified as key behavioural strategies to prevent HIV transmission in sub-Saharan Africa, particularly following recognition of the role that multiple concurrent sexual partnerships play in driving generalised HIV epidemics. We analysed social representations of fideli...
journal_title:SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliancepub_type: 杂志文章
doi:10.1080/17290376.2021.1950042
更新日期:2021-12-01 00:00:00
abstract::Long non-coding RNAs (lncRNAs) are the new regulators and biomarkers for various tumors. However, in cervical cancer (CC), the potential roles of lncRNAs are not well characterized. This research aimed at exploring the roles of MEOX2 antisense RNA 1(MEOX2-AS1) in CC progression and the underlying mechanisms. The exami...
journal_title:Bioengineeredpub_type: 杂志文章
doi:10.1080/21655979.2021.1947174
更新日期:2021-12-01 00:00:00
abstract::Sámi people report less satisfaction with healthcare services than the majority population in Norway, and report that they seldom encounter culturally adapted health services. This study investigates Sámi and Norwegian nurses' perspectives on culturally respectful and appropriate caring for Sámi patients in northern N...
journal_title:International journal of circumpolar healthpub_type: 杂志文章
doi:10.1080/22423982.2021.1948246
更新日期:2021-12-01 00:00:00
abstract::This study aimed to compare efficacy and safety of HepaSpheres and CalliSpheres in unresectable large hepatocellular carcinoma (HCC) patients. One hundred and twenty-seven unresectable large HCC patients receiving drug-eluting bead transarterial chemoembolization (DEB-TACE) treatment with CalliSpheres or HepaSpheres m...
journal_title:Drug deliverypub_type: 杂志文章
doi:10.1080/10717544.2021.1943057
更新日期:2021-12-01 00:00:00
abstract::Purpose: Adolescents with cerebral palsy may need a feeding tube due to feeding challenges, since nutritional intake and mealtimes may be negatively affected. The purpose of the study was to describe and better understand how one adolescent with cerebral palsy and her parents experienced mealtimes before and after a n...
journal_title:International journal of qualitative studies on health and well-beingpub_type: 杂志文章
doi:10.1080/17482631.2021.1942415
更新日期:2021-12-01 00:00:00
abstract::Antiretroviral therapy effectively prevents sexual and vertical transmission of HIV. Yet, some women living with HIV report having unmet needs for reproductive health care. This study measured the prevalence of women discussing reproductive goals with any current healthcare provider and assessed the effect of the curr...
journal_title:Sexual and reproductive health matterspub_type: 杂志文章
doi:10.1080/26410397.2021.1932702
更新日期:2021-12-01 00:00:00
abstract:BACKGROUND:Hazardous alcohol use significantly affects health and wellbeing in society. General practitioners (GPs) are uniquely positioned to address this problem by integrating early identification and brief intervention (EIBI) in daily practice. Unfortunately, EIBI implementation remains low. Community-oriented stra...
journal_title:The European journal of general practicepub_type: 杂志文章
doi:10.1080/13814788.2021.1936493
更新日期:2021-12-01 00:00:00
abstract::Diabetic glomerulopathy (DG) remains the prevalent microvascular complication and leading cause of shortened lifespan in type-2 diabetes mellitus (T2DM) despite improvement in hyperglycemia control. Considering the pivotal role of kidney in metabolism, using untargeted metabolomic techniques to globally delineate the ...
journal_title:Renal failurepub_type: 杂志文章
doi:10.1080/0886022X.2021.1937219
更新日期:2021-12-01 00:00:00
abstract::Purpose: In developed countries, diet-related health inequalities between people with different levels of socioeconomic advantage persist. However, there is limited qualitative evidence to inform the design of effective healthy eating (HE) strategies in socioeconomically disadvantaged populations (SDPs). The purpose o...
journal_title:International journal of qualitative studies on health and well-beingpub_type: 杂志文章
doi:10.1080/17482631.2021.1942416
更新日期:2021-12-01 00:00:00
abstract::In this research, we formulated new chemotherapeutic copper nanoparticles (Cu NPs) containing Allium noeanum Reut. ex Regel leaf for treating human endometrial cancer. For investigating the antioxidant activitiy, the 2,2-diphenyl-1-picrylhydrazyl (DPPH) test was used. MTT test was used on normal (Human umbilical vein ...
journal_title:Artificial cells, nanomedicine, and biotechnologypub_type: 杂志文章
doi:10.1080/21691401.2021.1926275
更新日期:2021-12-01 00:00:00
abstract:Background:The COVID-19 pandemic is placing significant pressure on national and international health organizations and the measures taken to combat it are having many impacts beyond health. At the same time, misleading communication practices and what has been called an "infodemic" by the World Health Organization hav...
journal_title:Integrative medicine researchpub_type: 杂志文章,评审
doi:10.1016/j.imr.2021.100731
更新日期:2021-12-01 00:00:00
abstract:BACKGROUND:Gut dysbiosis may be implicated in the pathogenesis of IgA nephropathy (IgAN) through immune and/or metabolite pathways. Fecal microbiota transplantation (FMT) could reestablish the micro-ecological balance in IgAN, although this has never been attempted before. We explored whether FMT could be efficacious i...
journal_title:Renal failurepub_type: 杂志文章
doi:10.1080/0886022X.2021.1936038
更新日期:2021-12-01 00:00:00
abstract::Purpose: To explore how people with mental illness experience recovery in the Clubhouse context, and which ingredients of the model they find active in promoting recovery.Methods: Hermeneutic-phenomenological design. Individual, semi-structured interviews with 18 Norwegian Clubhouse members. Systematic text condensati...
journal_title:International journal of qualitative studies on health and well-beingpub_type: 杂志文章
doi:10.1080/17482631.2021.1938957
更新日期:2021-12-01 00:00:00
abstract::Studies have shown the use of non-steroidal anti-inflammatory drugs, such as ibuprofen could reduce the risk of Alzheimer's disease. The drug-repurposing strategy offers a bright opportunity for these patients. Intranasal administration through the olfactory pathway provides noninvasive and direct drug delivery to the...
journal_title:Drug deliverypub_type: 杂志文章
doi:10.1080/10717544.2021.1937383
更新日期:2021-12-01 00:00:00
abstract::The purpose of this study was to investigate the impact and mechanism of microRNA miR-126 on brain injury induced by blood-brain barrier (BBB) damage in septic rats. We used cecal ligation and perforation (CLP) to create a rat model of sepsis. The experimental rats were randomly divided into Control group, CLP group, ...
journal_title:Bioengineeredpub_type: 杂志文章
doi:10.1080/21655979.2021.1937905
更新日期:2021-12-01 00:00:00